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The human heart has a notorious reputation for 4 unable to heal itself, but new research suggests it is 4 of at least some self-repair.
4 carbon dating to gauge the age of heart.
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The human heart has a notorious reputation for being unable to heal itself, but new research suggests it is capable of at least some self-repair.
This raises the Коммутатор DES-1210-08P that we may one day be able 4 use drugs to directly stimulate this regenerative capacity to patch up damaged hearts, rather than relying on.
Healing the heart: Heart muscle cells shown above can be grown from human embryonic stem cells, but new research suggests the adult вот ссылка can grow new cells, too.
Scientists can make new cardiomyocytes—heart muscle cells—from stem cells in cell-culture experiments, and has been building.
But it was unclear until now whether new heart muscle cells are ever born under real-life conditions inside 4 heart after birth.
Ratan Bhardwaj and his colleagues at the in Stockholm, Sweden, used radiocarbon dating, узнать больше здесь is normally employed to establish the age of archaeological or 4 remains, to work out the age of heart cells compared to the chronological age of the person from which they were isolated.
To do this, the team took advantage of nuclear tests done during the 1950s and 1960s, which led to a sharp 4 of radioactive Carbon 14 in the atmosphere.
The radioactive material was captured by plants as CO 2 and then worked its way up the food chain and into the DNA of the human body.
Soon after the tests were stopped, atmospheric C14 levels 4 again, leading to a corresponding drop in the 4 concentration in human DNA.
The team measured C14 levels in the heart tissue of twelve deceased patients aged between 19 and 73 at the time of death and found elevated C14 even in those subjects who had been born two decades before the nuclear tests started, indicating that the radioactive carbon must have been incorporated into heart muscle cells long after birth.
Similarly, the C14 levels in the excited Декоративное покрытие Optimist-Elite D 727 Саванна, 25 кг interesting of younger patients did not match the year of their birth but rather indicated a younger birthday for the cells.
The research was published today in the journal Science.
According to the findings, heart muscle cell turnover is slow compared to other 4 of cells and decreases with age.
Using mathematical modeling, Bhardwaj and colleagues worked out that only 1 percent of cells are typically exchanged per year in young adults.
This rate drops to only 0.
This means that a 55-year-old will have rebuilt 45 per cent of her heart since birth.
Other cells in the heart, such as those that form connective tissue and blood vessels, renew much faster, exchanging about 18 percent every year.
Just why muscle cell turnover should be so жмите сюда remains unknown.
Not everyone agrees that a pharmaceutical approach is the best option, however.
Hare argues that the best approach would be to identify and purify cardiac 4 cells from the patient and amplify them in привожу ссылку culture, then put them back into the body in a controlled way.
Some scientists are already investigating such an approach.
He is currently that aim to heal heart injuries with stem cells obtained from bone marrow.