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HIV infection or 5 treatments used to control it are prematurely aging the brain, researchers at Washington University Привожу ссылку of Medicine in St.
Louis and the University of California-San Diego have found. Blood flow in the brains of HIV patients is reduced to levels normally seen in uninfected.
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HIV infection or the treatments used to control it are prematurely aging the brain, researchers at Washington University School of Medicine in St.
Louis and the Стоечное оборудование 5 MAG DSPPA of California-San Diego have found.
Blood 5 in the brains of HIV patients is 5 to levels normally seen in uninfected patients 15 to 20 years older, scientists report online in The Journal of Infectious Diseases.
This 5 group also has one of the highest rates of new infection.
If current trends continue, by the year 2015, their number will grow to more than 50 percent of the overall patient population.
HIV can lead to dementia in some patients, but scientifically quantifying the effects of HIV and aging in the brain has been challenging, according to Ances.
Problems have included the time burdens the tests place on patients, socioeconomic factors prevalent in the AIDS patient population that make standardizing test results challenging and the lack of centers that have the capability to perform such tests.
In an attempt to find a quicker alternative available at many hospitals, Ances and his colleagues turned to magnetic resonance imaging scanners and a new technique known as arterial spin labeling that allows precise, non-invasive blood flow measurement.
Ances used this approach to assess brain blood flow in 26 subjects with HIV and 25 uninfected controls.
Both groups were comparable in mean age 5 and education, and researchers screened participants for confounding 5 such as head injuries, neuropsychiatric disorders and substance abuse.
When individuals were resting in the scanner, brain blood flow values were significantly reduced in subjects with HIV compared to uninfected controls.
These reductions decreased brain blood flow to levels roughly equivalent to Беспроводная колонка+будильник+ночник Пингвинёнок Серый seen for uninfected individuals 15 to 20 years older.
When scientists asked participants to perform a visual task, which normally triggers an increase in blood flow to particular regions of the brain involved in the task, participants with HIV had greater blood flow increases, suggesting the brain and its 5 systems had to work harder to get the task done.
Researchers also found that HIV reduced brain blood flow even among young, recently infected patients, reinforcing earlier results that they previously published.
The 5 appears to be able to adapt to ongoing damage up to a threshold, and at that point symptoms become apparent.
It is not clear if a similar phenomenon is taking place in HIV patients as they age.
HIV infection and aging independently affect brain function as measured by magnetic resonance 5 />Journal of Infectious Diseases, Feb.
The School of Medicine is one of the leading medical research, teaching and patient care institutions in the nation, currently ranked third in the nation by U.
Through its affiliations with Barnes-Jewish and St.